I usually sprayed foaming tire shine up in the wheel wells to make them look great, but now that I've found top of the line detailing products I just use their Grape Tire dressing up in there, works great.
One thing that sucks about my MCS is the fact that the wheel wells are carpeted, yes, carpeted, so I can't even spray anything up in there like I used to. I just spray my all purpose degreaser in there from time to time but always rinse out everytime!