I have a set of 275/30's in the back, and they are fine, but 45 is a pretty tall profile, I would be for sure to measure the clearance levels and make certain they won't rub. Does a local tire shop have anything of that size you can mount and try fitment? That's what I did with one of my other cars, it was a bit of a pain but well worth it in my mind. Just want to make sure at full suspension compression that they dont hit the body. Don't know if this helps, just my quick 2C.