Run nitrous and you'll toast the piston rings in a hurry at the least. At the most, you'll throw a rod, kill a bearing, crack a piston, the list goes on.
Friend of mine had a 75 shot on his integra type r. Very rare motor worth several thousand dollars. Everyone told him not to spray it. I have had 4 years of tuning experience with air / fuel trims. I monitored knock, fuel, exhaust temps, etc. Got it tuned out for a "safe range". That motor lasted maybe a year.
He developed a tick, which fastly turned into lower oil pressure, and a bad knock by the end of the week. He had to pull the motor, I think he went 20 over on the piston walls and had to go with forged internals as the factory pistons wouldn't compensate for the new clearance due to the scoring on the walls.
You want to spray something? Go buy a junk honda and give it a 200 shot. It should be fun for a few passes. Otherwise don't bother.