When I wash the car, which is rare (limited use, sunshine only, garage kept) I'll clean the wheels with Meguiar's Hot Rims All Wheel Cleaner and a soft wheel brush that can reach deep between the spokes. Between washes I use Meguiar's Quik Wheel Detailer but I do keep a coat of wax on them, usually Meguiar's M20 Polymer Sealant because of its cleaning ability and longevity.

A couple times a year I'll pull them off the car and clean them inside and out (or is that front and back?) with Meguiar's Wheel Brightener from our Pro Detailer line. Fantastic stuff for removing badly set in brake dust.

I have to say though, since swapping to Posi-Quiet ceramic brake pads cleanup is a snap. Best mod I've ever done to this car - by a long shot.