I-75 for sure! It's a bit boring, but it gets you there quickly. I've driven it from Toronto to St. Pete Beach about 40 or more times. Decidedly faster and safer! I love I-77 because it is much prettier, but there sure are alot of deer on that highway and the odds of smacking one are pretty good in comparison to the 75. Those things stand literally 3 feet off the roadway and don't even flinch when a semi blasts by. Downright scarry to be honest.

Drive safely and see you there!