I would not have any concerns about flying the Aerocar regardless of age. The Airworthiness certificate would be the deciding factor. Airworthiness is the measure of an aircraft's suitability for safe flight. Certification of airworthiness is conferred by a certificate of airworthiness from the state of aircraft registry national aviation authority, and is maintained by performing the required maintenance actions. The airworthiness certificate remains valid as long as the aircraft meets its approved type design, is in a condition for safe operation and maintenance, preventative maintenance, and alterations are performed in accordance with 14 CFR parts 21, 43, and 91. ie; annual or 100hr, depends on how you operate the aircraft. Most private aircraft use the annual requirement. Certainly aircraft logbooks would be reviewed and any write-ups cleared before flight, standard procedure for any aircraft regardless of age.

I would consider changing the wheels to magnesium for weight purposes [ American Racing mags] Being a purest however I would leave it alone and swap wheels only when taking it up for flight.