There is really nothing to tune as this is not your grandfathers car, any faults should show up as a red engine light on the dash and the problem probably can be found by reading the code with a code reader. Some faults do not result in a red light, so use the reader for hidden or possible future faults. Adhering to the service routine schedule is about all you can do, although the plug, oils and transmission oil and filter mileages should be halved at least. Only use Bosch sensors and Mobil-1 oil or a similar oil etc. Do not go cheap, even the coolant type is specified so use it.
Physically the cars steering, drive train and suspension etc could be looked at by a good mechanic, preferably one with Mercedes experience. All answers to your questions can be found on this forum, you just have to sort the wheat from the chaff.
Good luck and welcome.