Bill, I really like this idea and would like to help plan more on this. Like RJ said, we can make this at least a three day event. Some things I was thinking about (all open for debate of course and hoping to draw some out of staters):

Day One:
Leave Denver (I-25/E-470) @ 8:00AM
Stop at the Garden of the Gods (55 miles) - meet and greet and drive around park - leave by 10:30AM.
Stop at K-Bobs for lunch in Canon City (50) miles - leave at 1:15PM
Stop at the Royal Gorge - 11 miles (maybe take the train at Buckskin Joes. Better view of the bridge and cheaper). Leave @ 3:30
Stop in Gunnison for the evening (115 miles) - Arrive around 6PM.
Dinner in Gunnison
Route:
Garden of the Gods, Colorado Springs, CO 80907 to Gunnison, CO - Google Maps

Day Two:
Leave Gunnison around 8:00AM
Stop at Black Canyon of the Gunnison National Park (68 miles) - Leave @10:30 AM
Lunch in Montrose (nice Mexican place downtown, 19 miles) - Leave @ 12:30PM
Drive to Glenwood Springs via Delta and Cedaredge to go over Grand Mesa (curvey roads! - 143 miles) arrive around 4-5PM.
Dinner/Lodge in Glenwood Springs for the evening
Route:
Gunnison, CO to Glenwood Springs, CO - Google Maps

Day three:
Leave Glenwood Springs @10AM
Take I-70 to Dillon (92 miles)
Lunch - Leave @ 1:15PM
Take US 6 over Loveland Pass and Stop in Georgetown (32 miles) - Perhaps we can site-see or take the Georgetown Loop
Head to Denver and home
Route map:
Glenwood Springs, CO to Georgetown, CO - Google Maps