NO.
You WILL lose most of the coolant, so you might as well do a full flush and replace with 50/50 distilled water and Zerex G05.
The radiator has a drain plug bottom driver side.
HINT: as you remove bolts from the old water pump, place them in the corresponding hole in the new pump. When you have the old pump removed, then transfer them back to it. When installing the new pump, you then will know which bolt goes where.
I had no problem with air bleeding on my NA, don't know about SRT6's.