My first 2005 was a Garage Queen with 13,351 miles on it. In the year I owned it, I ran it up to something around 22,000 miles. I then bought a Graphite Roadster with 44,000 and drove it to 116,000 with only two issues:

Sticky key - locked up at a gas station, I knew about the fix but had just bought the car.
CPS went out - engine restarted and I changed the part that evening.

The car was lost in an accident (other driver at fault).

The third car is my present SE. It was a low miles car that had sat a lot. It has needed some TLC, nothing major and it has never let me down or left me stranded.

I will say this: The more the car is driven, the more reliable it is. I am considering selling the truck once I move to Dallas and buying a high miles automatic coupe as a daily driver - the Crossfire would be faster than the truck and people out there drive fast!

YES, you read that right, I'm, actually thinking of buying an AUTOMATIC.